Activity Description:

This presentation will describe several new studies and publications regarding the use of whole blood or low titer O whole blood (LTOWB) in trauma patients. Early and late survival in trauma patients receiving WB as compared to component therapy will be explored. Additionally, the utility of whole blood in certain situations such as use in children and in penetrating versus blunt injuries will be discussed.  Lastly, the effect of the amount of whole blood used in the resuscitation versus the entire amount of transfused products will be evaluated and the effect on mortality will be discussed. Finally, since O- RBCs and O- whole blood are in extremely short supply, O+ RBCs and O+ whole blood are frequently used instead regardless of the Rh status of the trauma patient. The frequency of anti-D development in trauma patients will be discussed and ethical considerations around Rh positive products will be discussed as well.

Target Audience: 

This course is designed for hospitalists, nurse practitioners, physician assistants, advance practice nurses, registered nurses, allied health professionals, physicians and residents.

Learning Objectives:

• Describe the differences in outcomes of whole blood versus component therapy use in trauma patients.
• Summarize the effect of whole blood use in penetrating versus blunt injury in trauma patients on mortality.
• Identify the risk and benefit of using O+ RBC and O+ whole blood in all trauma patients.

Moderator:

Speaker: Amy Schmidt, MD, PhD

Non-faculty contributors and others involved in the planning, development and editing/review of the content have no relevant financial relationships to disclose with ineligible companies.*

*Ineligible companies – Companies whose primary business is producing, marketing, selling, re-selling or distributing healthcare products used by or on patients.

Accreditation:

The HCA Healthcare Continental Division is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. 

Credit Designation:

The HCA Healthcare Continental Division designates this live activity for a maximum of 1.0 AMA PRA Category 1^TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Commercial Support:  

This Activity was developed without support from any ineligible company.*The ACCME defines ineligible companies as those whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. Note: The ACCME does not consider providers of clinical service directly to patients to be commercial interests – unless the provider of clinical services is owned, or controlled by, and ACCME defined ineligible company.

Disclosure: 

The HCA Healthcare Continental Division is committed to providing CME that is balanced, objective, and evidenced-based. In accordance with the Accreditation Council for Continuing Medical Education Standards for Integrity and Independence all parties involved in content development are required to disclose all conflicts of interest with ACCME defined ineligible companies. The HCA Healthcare Continental Division has identified, reviewed, and mitigated all conflicts of interest that speakers, authors, course directors, planners, peer reviewers, or relevant staff disclose prior to the delivery of any educational activity. The CME planning committee who are in a position to control the content of this CME Activity, have no relevant financial relationships with ineligible companies to disclose.